Antiviral Activity Of Ribosome Inactivating Proteins In Medicine

Author(s): Bijal A. Parikh, Nilgun E. Tumer.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 4 , Issue 5 , 2004

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Pokeweed antiviral protein and several other ribosome inactivating proteins are effective against a broad range of viruses. Recent results have shown that their enzymatic activity is not limited to depurination of the large rRNA, they can depurinate other nucleic acids, including viral RNAs. Antiviral activity of RIPs is summarized here in light of their novel activities and recent developments in the field.

Keywords: antiviral activity, ribosome inactivating proteins, rrna, rips

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Article Details

Year: 2004
Page: [523 - 543]
Pages: 21
DOI: 10.2174/1389557043403800
Price: $58

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