Genomic Strategies in Transplantation “The Right Drug for the Right Patient”

Author(s): Bernd Schroppel.

Journal Name: Current Pharmacogenomics
Continued as Current Pharmacogenomics and Personalized Medicine

Volume 2 , Issue 2 , 2004

Abstract:

Purpose of review: The purpose of this review is to summarize recent advances in the area of genetic polymorphisms in genes affecting immunosuppressive drug bioavailability with a specific emphasis on solid organ transplantation. Recent findings: Due to recent advances in molecular techniques, there has been an abundance of publications describing genetic variability in molecules relevant to pharmacogenetics. The initial studies in the field of transplantation demonstrate some associations between polymorphisms in these candidate genes with outcomes in organ transplantation.

Keywords: Transplantation, genetic polymorphisms, immunosuppressive drug, bioavailability

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Article Details

VOLUME: 2
ISSUE: 2
Year: 2004
Page: [175 - 184]
Pages: 10
DOI: 10.2174/1570160043377600
Price: $58

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