Synthesis and Stability of 1-Phenylethenyl Phosphate Derivatives and their Phosphoryl Transfer Activity

Author(s): Tomohisa Moriguchi, Kazuhisa Okada, Kohji Seio, Mitsuo Sekine.

Journal Name: Letters in Organic Chemistry

Volume 1 , Issue 2 , 2004

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Abstract:

1-Phenylethenyl phosphate derivatives of the monoester type were synthesized via the Perkow reaction. Among them, 2-(2,4-difluorophenyl)ethenyl phosphate was found to be obtained as a pure salt. It turned out that this compound and 2-phenylethenyl phosphate can transfer their phosphoryl groups to AMP in pyridine at elevated temperatures to give ADP.

Keywords: enol phosphate, phosphoryl transfer, phosphorylation, perkow reaction

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Article Details

VOLUME: 1
ISSUE: 2
Year: 2004
Page: [140 - 144]
Pages: 5
DOI: 10.2174/1570178043488482
Price: $58

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