4-Alkoxy-1,1,1-Trichloro-3-Alken-2-ones: Preparation and Applications in Heterocyclic Synthesis

Author(s): Marcos A. P. Martins , Wilson Cunico , Claudio M. P. Pereira , Adilson P. Sinhorin , Alex F. C. Flores , Helio G. Bonacorso , Nilo Zanatta .

Journal Name: Current Organic Synthesis

Volume 1 , Issue 4 , 2004

Become EABM
Become Reviewer

Abstract:

The preparation of 4-alkoxy-1,1,1-trichloro-3-alken-2-ones (enones), important synthetic tools for the heterocyclic synthesis, from cheap and easily accessible starting materials, is reported. The applications of the enones in the synthesis of isoxazoles, pyrazoles, pyrimidines and other heterocycles are also reported. This review was grouped into two main sections: (i) synthesis of 4-alkoxy-1,1,1-trichloro-3-alken-2-ones and derivatives and (ii) applications of 4-alkoxy-1,1,1-trichloro-3-alken-2-ones in heterocyclic synthesis.

Keywords: enones, enol ethers, acetals, trichloromethyl-compounds, isoxazoles, pyrazoles, pyrimidines

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 1
ISSUE: 4
Year: 2004
Page: [391 - 403]
Pages: 13
DOI: 10.2174/1570179043366611
Price: $58

Article Metrics

PDF: 13