Title: Rhenium-188 and Copper-67 Radiopharmaceuticals for the Treatment of Bladder Cancer
VOLUME: 4 ISSUE: 1
Author(s): M. Frier
Affiliation:Radiopharmacy Unit,Queens Medical Centre, Nottingham, UK
Keywords:Rhenium-188, Copper-67, Bladder, Cancer, Radioimmunotherapy
Abstract: The favourable nuclear properties of copper-67 and rhenium-188 for therapeutic application are described, together with methods for the chemical synthesis of a number of derivatives. Survival from invasive bladder cancer has changed little over the past 20 years. The intravesicular administration of Cu-67 or Re-188 radiopharmaceuticals in the treatment of bladder cancer offers some promise for improvement in this situation.