Titanocene(II)-Promoted Reaction of Thioacetals with Styrenes: Stereoselective Formation of (E)-β-Substituted Styrene Derivatives

Title: Titanocene(II)-Promoted Reaction of Thioacetals with Styrenes: Stereoselective Formation of (E)-β-Substituted Styrene Derivatives

Volume: 1 Issue: 4

Author(s): Akira Tsubouchi, Emi Nishio, Koutaro Arai and Takeshi Takeda

Affiliation:

Keywords: alkenes, elimination, carbene complexes, styrenes, titanocene(II)

Abstract: (E)-β-Substituted styrenes were obtained stereoselectively by the titanocene(II)-promoted desulfurizative coupling of thioacetals with styrenes. It is suggested that the reaction proceeds through the regioselective formation of a titanacyclobutane intermediate, followed by ?-elimination.

Cite this article as:

Tsubouchi Akira, Nishio Emi, Arai Koutaro and Takeda Takeshi, Titanocene(II)-Promoted Reaction of Thioacetals with Styrenes: Stereoselective Formation of (E)-β-Substituted Styrene Derivatives, Letters in Organic Chemistry 2004; 1 (4) . https://dx.doi.org/10.2174/1570178043400325