Total Syntheses of Macrosphelides C, F, G and H

Author(s): Yuichi Kobayashi, Yong-Gang Wang, Hukum P. Acharya.

Journal Name: Letters in Organic Chemistry

Volume 1 , Issue 4 , 2004

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Abstract:

The title macrosphelides were synthesized by using two-step conversion of furans into γ-oxo-α,β- unsaturated carboxylic acids as a key step. In the case of macrosphelide H, AcCH2 group at C(3) was constructed from CH2=CHCH2 by Wacker oxidation under modified conditions.

Keywords: macrosphelide, asymmetric synthesis, wacker oxidation, furan, furan oxidation

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Article Details

VOLUME: 1
ISSUE: 4
Year: 2004
Page: [297 - 307]
Pages: 11
DOI: 10.2174/1570178043400424
Price: $65

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