α-Amylase Inhibitors were isolated from Ficus sp. (Gameleira) seeds by acetone fractionation and Sephadex G-50. Two inhibitors (α-PPAI and α-ZSAI) were tested against α-amylases from coleopteran larvae. α-PPAI was active to α-amylases of Callosobruchus maculatus (52%) and Zabrotes subfasciatus (53%). α-ZSAI was strongly active to Z. subfasciatus (100%) of and Mimosestes mimosae (98%). The α-ZSAI is a glycoprotein of ∼50kDa with an IC50 value of 0.074 μg μl-1.
Keywords: Ficus sp,, Zabrotes subfasciatus,, Callosobruchus macutatus,, Mimosestes mimosae,
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