Abstract
Tuberculosis represents the main cause of mortality due to a single pathogen infection. Advances in anti-tuberculosis therapies are urgently required both for treatment of the 8-12 million new cases of tuberculosis leading to 2 million deaths each year, as well as for the 2 billion individuals already infected with M. tuberculosis, who are at the risk of developing disease. The present review summarizes the actually available information about currently existing therapies and perspectives for future innovative therapeutic approaches.
Keywords: tuberculosis, mycobacteria, therapeutics, immune-modulators
Letters in Drug Design & Discovery
Title: Tuberculosis Therapeutics: Past Achievements, Present Road-Blocks and Future Perspectives
Volume: 1 Issue: 4
Author(s): Sanjay K. Garg, Marilina B. Santucci, Fouad Seghrouchni, Cesare Saltini, Prakash S. Bisen, Vittorio Colizzi and Maurizio Fraziano
Affiliation:
Keywords: tuberculosis, mycobacteria, therapeutics, immune-modulators
Abstract: Tuberculosis represents the main cause of mortality due to a single pathogen infection. Advances in anti-tuberculosis therapies are urgently required both for treatment of the 8-12 million new cases of tuberculosis leading to 2 million deaths each year, as well as for the 2 billion individuals already infected with M. tuberculosis, who are at the risk of developing disease. The present review summarizes the actually available information about currently existing therapies and perspectives for future innovative therapeutic approaches.
Export Options
About this article
Cite this article as:
Garg K. Sanjay, Santucci B. Marilina, Seghrouchni Fouad, Saltini Cesare, Bisen S. Prakash, Colizzi Vittorio and Fraziano Maurizio, Tuberculosis Therapeutics: Past Achievements, Present Road-Blocks and Future Perspectives, Letters in Drug Design & Discovery 2004; 1 (4) . https://dx.doi.org/10.2174/1570180043398515
DOI https://dx.doi.org/10.2174/1570180043398515 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Intraocular Inflammation and Systemic Immune-Mediated Diseases
Current Immunology Reviews (Discontinued) A Tour of Unsupervised Deep Learning for Medical Image Analysis
Current Medical Imaging Fluorinated Compounds Against Mycobacterium tuberculosis
Current Topics in Medicinal Chemistry Sphingolipids in Cell Signaling: Their Function as Receptor Ligands, Second Messengers, and Raft Constituents
Current Immunology Reviews (Discontinued) Synthesis and Antitubercular Screening of Some Novel 4H-1,4- Benzothiazines and their Sulfones Under Environment Benign Solvent Free Conditions as Future Anti-Tubercular Agents
Combinatorial Chemistry & High Throughput Screening Vitamin D: Evolutionary, Physiological and Health Perspectives
Current Drug Targets Ureas: Applications in Drug Design
Current Medicinal Chemistry Fatty Acids - Induced Lipotoxicity and Inflammation
Current Drug Metabolism EDITORIAL: Vaccinology in the 21st century
Current Topics in Medicinal Chemistry Transcription Analysis and Small Non-Protein Coding RNAs Associated with Bacterial Ribosomal Protein Operons
Current Medicinal Chemistry Recent Advances in Metabolomics
Current Metabolomics ent-Abietane Lactones from Euphorbia
Mini-Reviews in Medicinal Chemistry Biological and Chemical Diversity of Coral-Derived Microorganisms
Current Medicinal Chemistry Lipid-Based Nanocarriers for Cutaneous Leishmaniais and Buruli Ulcer Management
Current Pharmaceutical Design Single Amino Acid Repeats Connect Viruses to Neurodegeneration
Current Drug Discovery Technologies Inhaled Biologics: From Preclinical to Product Approval
Current Pharmaceutical Design A Brief Overview of Antimicrobial Peptides Containing Unnatural Amino Acids and Ligand-Based Approaches for Peptide Ligands
Current Topics in Medicinal Chemistry Structure- and Ligand-Based Structure-Activity Relationships for a Series of Inhibitors of Aldolase
Current Computer-Aided Drug Design Derivatives of 3-Isoxazolecarboxylic Acid Esters - A Potent and Selective Compound Class against Replicating and Nonreplicating Mycobacterium tuberculosis
Current Topics in Medicinal Chemistry Anti Tumor Necrosis Factor-a Monoclonal Antibody (Infliximab) Therapy in Patients with Inflammatory Bowel Disease (IBD): Applications and Side Effects
Drug Design Reviews - Online (Discontinued)