The Intracellular Distribution and Secretion of Endopeptidases 24.15 415 (Ec and 24.16 (Ec

Author(s): Emer S. Ferro, Flavia R. Carreno, Camila Goni, Paula A.G. Garrido, Alessander O. Guimaraes, Leandro M. Castro, Vitor Oliveira, Mauricio C. Araujo, Vanessa Rioli, Marcelo D. Gomes, Jose Domingues Fontenele-Neto, Stephen Hyslop.

Journal Name: Protein & Peptide Letters

Volume 11 , Issue 5 , 2004

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Endopeptidase 24.15 (EC; EP24.15) and endopeptidase 24.16 (EC; EP24.16) are enzymes involved in general peptide metabolism in mammalian cells and tissues. This review will focus on morphological and biochemical aspects related to the subcellular distribution and secretion of these homologous enzymes in the central nervous system. These are important issues for a better understanding of the functions of EP24.15 and EP24.16 within neuroendocrine systems.

Keywords: endopeptidase, exocytosis, neurolysin, peptide metabolism, thimet-oligopeptidase, unconventional, secretion, fusion pore

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Article Details

Year: 2004
Page: [415 - 421]
Pages: 7
DOI: 10.2174/0929866043406706
Price: $58

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