Exploring the Phosphoproteome with Mass Spectrometry

Author(s): Eric C. Peters, Ansgar Brock, Scott B. Ficarro.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 4 , Issue 3 , 2004

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Abstract:

Protein phosphorylation is a reversible post-translational modification crucial in the control of numerous regulatory pathways. Understanding the highly interconnected nature of such networks requires new broader-scale analysis techniques. This report summarizes recent advances in the use of mass spectrometry to assess phosphorylation events in ever more complex systems.

Keywords: Phosphoproteome, phosphorylation, spectrometry

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Article Details

VOLUME: 4
ISSUE: 3
Year: 2004
Page: [313 - 324]
Pages: 12
DOI: 10.2174/1389557043487330
Price: $58

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