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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Synthetic Approaches to the 2003 New Drugs

Author(s): Kevin K.- C. Liu, Jin Li and Subas Sakya

Volume 4, Issue 10, 2004

Page: [1105 - 1125] Pages: 21

DOI: 10.2174/1389557043402900

Price: $65

Abstract

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing new future drugs. To these ends, this review covers the syntheses of 23 NCEs marketed in 2003.

Keywords: synthesis, new drug, new chemical entities, medicine, therapeutic agents


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