Letters in Drug Design & Discovery

G. Perry
University of Texas
San Antonio, TX
USA
Email: lddd@benthamscience.org

Back

Prevention of Cell Damage in Ischaemic-Reperfusion: Mitochondrial Respiratory Chain as a Pharmacological Target

Author(s): D. Morin, R. Zini, J. P. Tillement, A. Berdeaux.

Abstract:

Ischaemic diseases, a major public health problem worldwide, are associated with a decrease in oxygen supply to mitochondria that impairs respiration, energy production and constitute stimuli for cell death. This paper summarises the pharmacological strategies targeting the mitochondrial respiratory chain, which represents an interesting therapeutic perspective.

Keywords: Ischaemia, reperfusion, mitochondrion, respiratory chain, atp, anti-ischaemic drugs

Order Reprints Order Eprints Rights & PermissionsPrintExport

Article Details

VOLUME: 1
ISSUE: 3
Year: 2004
Page: [279 - 284]
Pages: 6
DOI: 10.2174/1570180043398803
Price: $58