Armed Imidazo [1,2-a] Pyrimidines (Pyridines): Evaluation of Antibacterial Activity
Imidazopyridines and imidazopyrimidines have been prepared and tested for their antibacterial activity in vitro. Structure activity relationship studies indicate (SAR) that a modulation of both natures of arm in position 3 and atom in position 8 of these compounds has a direct impact on the antibacterial activity.
Keywords: Imidazo[1,2-a]pyrimidines., imidazo[1,2-a]pyridines, antibacterial agents, functionalised arms, n-ligands, mycobacterium tuberculosis
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