Letters in Drug Design & Discovery

G. Perry
University of Texas
San Antonio, TX
USA
Email: lddd@benthamscience.org

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Armed Imidazo [1,2-a] Pyrimidines (Pyridines): Evaluation of Antibacterial Activity

Author(s): A. Anaflous, N. Benchat, M. Mimouni, S. Abouricha, T. Ben-Hadda, B. El-Bali, A. Hakkou, B. Hacht.

Abstract:

Imidazopyridines and imidazopyrimidines have been prepared and tested for their antibacterial activity in vitro. Structure activity relationship studies indicate (SAR) that a modulation of both natures of arm in position 3 and atom in position 8 of these compounds has a direct impact on the antibacterial activity.

Keywords: Imidazo[1,2-a]pyrimidines., imidazo[1,2-a]pyridines, antibacterial agents, functionalised arms, n-ligands, mycobacterium tuberculosis

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Article Details

VOLUME: 1
ISSUE: 3
Year: 2004
Page: [224 - 229]
Pages: 6
DOI: 10.2174/1570180043398885
Price: $58