Current Rheumatology Reviews

Dr. Serena Guiducci  
Department of Biomedicine, Division of Rheumatology
University of Florence
Florence
Italy

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Hyperuricemia and Coronary Artery Disease

Author(s): Christine Halligan, Eric L. Matteson.

Abstract:

Hyperuricemia is strongly associated with several known risk factors for cardiac disease including hypertension, diabetes mellitus, hypercholesterolemia and obesity. Despite this association between hyperuricemia and these coronary artery disease risk indicators, most studies have failed to demonstrate a direct causal relationship between hyperuricemia itself and cardiovascular disease. It has been suggested that insulin resistance and endothelial dysfunction may be a common denominator in linking cardiovascular disease and hyperuricemia.

Keywords: hyperuricemia, rheumatoid arthritis, coronary artery disease

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Article Details

VOLUME: 1
ISSUE: 2
Year: 2005
Page: [193 - 197]
Pages: 5
DOI: 10.2174/1573397054023128
Price: $58