Synthesis of β-Ketonitriles from 3-Bromoisoxazoles

Author(s): Martin G. Kociolek, Nicholas G. Straub, Elizabeth J. Marton.

Journal Name: Letters in Organic Chemistry

Volume 2 , Issue 3 , 2005

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Abstract:

A series of substituted 3-bromoisoxazoles were ring opened with either molybdenum hexacarbonyl or iron (II)chloride tetrahydrate to give β -ketonitriles in good yields.

Keywords: isoxazole, ketonitrile, molybdenum hexacarbonyl, ferrous chloride, reductive ring opening

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Article Details

VOLUME: 2
ISSUE: 3
Year: 2005
Page: [280 - 282]
Pages: 3
DOI: 10.2174/1570178053765302
Price: $65

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