Abstract
Guanacastepene A is a novel diterpene isolated from cultures of an unidentified fungus growing on the tree Daphnopsis americana. Its new molecular structure and its interesting biological property as antibiotic render this compound an attractive synthetic target. This review aims to summarise the chemistry associated to the construction of this molecule including synthetic strategies developed for the elaboration of related model systems.
Keywords: bacterial strains, antibiotic, bioactive metabolites, daphnosis americana, microorganisms, nmr experiments, crystallography
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
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