Role of Endogenous Cannabinoids in Cognition and Emotionality

Author(s): Carsten T. Wotjak.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 5 , Issue 7 , 2005

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Novel pharmacological tools and the generation of null-mutants enabled the elucidation of the role of endocannabinoids in cognition and emotionality of rats and mice. Endocannabinoids seem to limit memory retention, to facilitate memory extinction and to ensure adequate coping with stressful situations. A selective potentiation of these actions may lead to novel pharmacotherapies for human anxiety disorders.

Keywords: learning, memory, review, anxiety, fear, stress, faah, cb, trpv, vr

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Article Details

Year: 2005
Page: [659 - 670]
Pages: 12
DOI: 10.2174/1389557054368763
Price: $65

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