Letters in Drug Design & Discovery

G. Perry
University of Texas
San Antonio, TX
USA
Email: lddd@benthamscience.org

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Design of a New Phosphate Binder, Anion Exchange Resin, Based on Microcalorimeter Measurements

Author(s): Hiroyoshi Inoue, Sho-ichi Yamagishi.

Abstract:

It has been suggested that resin wettability is advantageous for dietary phosphate binding in the gastrointestinal tract. To evaluate the effect of anion exchange resin wetting properties on in vivo phosphate binding ability, four types of ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium anion exchange resins (EGDMA-4VP) were synthesized.

Keywords: phosphate binding, wetting, immersion heat, ethylene glycol dimethacrylate cross-linking 4-vinylpyridinium, sevelamer hci, gastrointestinal content

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Article Details

VOLUME: 2
ISSUE: 3
Year: 2005
Page: [250 - 254]
Pages: 5
DOI: 10.2174/1570180053765138
Price: $58