A Centennial Methodology for the Preparation of Heterocyclic Compounds: The Intramolecular Coiodination of Alkenes with Internal Oxygenated Nucleophiles

Author(s): Flavia Martins da Silva, Joel Jones Junior, Marcio C.S. de Mattos.

Journal Name: Current Organic Synthesis

Volume 2 , Issue 3 , 2005

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Abstract:

A review on the intramolecular coiodination of alkenes with internal oxygenated nucleophiles (alkenols, unsaturated ethers, carboxylic acids and derivatives) is presented. The reactions are discussed with emphasis in the preparation of iodotetrahydrofurans, iodotetrahydropyrans and iodolactones and their utilization in organic synthesis. The intramolecular coiodination of alkenes with less common oxygenated nucleophiles (unsaturated carbonates, phosphates, isoxazolines, uretanes, hydroperoxides and silenols) is also presented.

Keywords: cohalogenation, cyclofunctionalization, iodocyclization, alkenes, organic synthesis

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Article Details

VOLUME: 2
ISSUE: 3
Year: 2005
Page: [393 - 414]
Pages: 22
DOI: 10.2174/1570179054368491
Price: $58

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