Selected Recent Advances in the Stereoselective Synthesis of Isoquinoline and β-Carboline Derivatives with the Use of Chiral Auxiliaries of Natural Origin

Author(s): Zbigniew Czarnocki, Aleksandra Siwicka, Joanna Szawkalo.

Journal Name: Current Organic Synthesis

Volume 2 , Issue 3 , 2005

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Various aspects of stereoselective synthesis of tetrahydroisoquinolines and tetrahydro-β-carbolines with the use of natural compounds as chirality sources are reviewed. The following low molecular weight substrates are considered: carbohydrates, isoprenoids, hydroxyacids, alkaloids and amino acids. Examples of various synthetic methodologies that employ the above derivatives as chiral building blocks, chiral auxiliaries or chiral ligands are presented.

Keywords: stereochemistry, alkaloids, pictet-spengler, bischler-napieralski, enantiomers, diastereomers

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Article Details

Year: 2005
Page: [301 - 331]
Pages: 31
DOI: 10.2174/1570179054368527
Price: $58

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