A Mild and Efficient Synthesis of Disecondary Phosphines Using CsOH: Efforts Toward Phosphine Macrocycles

Author(s): Matthew T. Honaker, Ralph N. Salvatore.

Journal Name: Letters in Organic Chemistry

Volume 2 , Issue 2 , 2005

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A mild and improved synthesis of disecondary phosphines PhPH(CH2)nPHPh (where n = 1-6), have been prepared. In the presence of phenylphosphine, cesium hydroxide, activated 4 Å molecular sieves and DMF, numerous dialkyl halides reacted efficiently to produce various disecondary phosphines exclusively at room temperature.

Keywords: primary phosphine, cesium hydroxide monohydrate, dialkyl halide, disecondary phosphine, phosphine macrocycle

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Article Details

Year: 2005
Page: [198 - 200]
Pages: 3
DOI: 10.2174/1570178053202874
Price: $65

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