A Very Short and Efficient Synthesis of Preclamol

Author(s): Arnault de Filippis, Domingo Gomez Pardo, Janine Cossy.

Journal Name: Letters in Organic Chemistry

Volume 2 , Issue 2 , 2005

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Abstract:

A very short and efficient synthesis of preclamol is described. The key step is the palladiumcatalysed arylation of the zinc enolate of N-propyl-2-piperidinone.

Keywords: preclamol, arylations, lactams, palladium, zinc, coupling reaction

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Article Details

VOLUME: 2
ISSUE: 2
Year: 2005
Page: [136 - 138]
Pages: 3
DOI: 10.2174/1570178053202883
Price: $65

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