Knowledge-Driven Lead Discovery

Author(s): Bernard Pirard .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 5 , Issue 11 , 2005

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Abstract:

Virtual screening encompasses several computational approaches which have proven valuable for identifying novel leads. These approaches rely on available information. Herein, we review recent successful applications of virtual screening. The extension of virtual screening methodologies to target families is also briefly discussed.

Keywords: virtual screening, chemical biology, chemogenomics, lead discovery, similarity searching, pharmacophore, data mining, docking

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Article Details

VOLUME: 5
ISSUE: 11
Year: 2005
Page: [1045 - 1052]
Pages: 8
DOI: 10.2174/138955705774575237
Price: $58

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