Current Status and Future Possibilities of Nitric Oxide-Donor Drugs: Focus on S-Nitrosothiols

Author(s): H. H. Al-Sa'doni, A. Ferro.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 5 , Issue 3 , 2005

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Abstract:

Drugs which release nitric oxide (NO) have great therapeutic potential. The organic nitrates and sodium nitroprusside have been used in cardiovascular therapeutics for many years, but several drawbacks limit their usefulness. In this review, we consider novel and potential future developments in NO-donor drugs, and the possible clinical usefulness of such compounds.

Keywords: nitric oxide, nitric oxide donors, s-nitrosothiols, therapeutics

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Article Details

VOLUME: 5
ISSUE: 3
Year: 2005
Page: [247 - 254]
Pages: 8
DOI: 10.2174/1389557053175399
Price: $58

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