Current Nutrition & Food Science

Undurti N. Das  
UND Life Sciences
Shaker Heights
OH 44120


Let Them Eat Cake

Author(s): Jane Durga, Petra Verhoef.


Folate, a B vitamin found almost ubiquitously in foods, is required for de novo nucleotide synthesis and methylation reactions in our body. A shortage of folate can lead to macrocytic anemia, however, extra folic acid, the synthetic form of folate, is considered to be a modern day panacea for a variety of diseases, specifically vascular disease. This review summarizes the evidence from randomized controlled trials and illustrates the weak foundation on which health claims regarding the possible beneficial effect of extra folic acid for vascular disease are based. It is prudent for public health policy makers to await trials--the conventional golden standard by which to test causality--before deciding on folic acid fortification for the general population.

Keywords: folic acid, b vitamin, natural foods, antioxidant, amino acid

Order Reprints Order Eprints Rights & PermissionsPrintExport

Article Details

Year: 2005
Page: [35 - 40]
Pages: 6
DOI: 10.2174/1573401052953221