The Chiral N-Monosubstituted 1,2-diphenyl-2-aminoethanols Promoted Enantioselective Diethylzinc Addition to In Situ Formed Imines

Author(s): W.- W. Yang, L.- F. Cun, Y.- G. Zhi, A.- Q. Mi, Y.- Z. Jiang, L.- Z. Gong.

Journal Name: Letters in Organic Chemistry

Volume 2 , Issue 7 , 2005

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Abstract:

The use of easily accessible N-monosubstituted 1,2-diphenyl-2-aminoethanols as ligands to promote the asymmetric addition of diethylzinc to alkyl- and arylimines generated in situ from the precursors provided optically active N-diphenylphosphinylamines with enantioselectivities of up to 96% ee.

Keywords: asymmetric catalysis, amino alcohols, diethylzinc addition, imines

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Article Details

VOLUME: 2
ISSUE: 7
Year: 2005
Page: [605 - 607]
Pages: 3
DOI: 10.2174/157017805774296939
Price: $65

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