Syntheses of Carbamate Derivatives of Quercetin by Reaction with Amino Acid Ester Isocyanates

Author(s): X. Wu, L. Cheng, D. Xiang, Y. Wei.

Journal Name: Letters in Organic Chemistry

Volume 2 , Issue 6 , 2005

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Abstract:

Synthesis of amino acid carbamate derivatives of quercetin from partly protected quercetin and amino acid esters utilizing triphosgene as an auxiliary reagent was studied. A series of quercetin derivatives were obtained regioselectively by reaction with amino acid ester isocyanates under mild conditions and in high yields.

Keywords: quercetin, flavonoid, tirphosgene, carbamate, isocyanate

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Article Details

VOLUME: 2
ISSUE: 6
Year: 2005
Page: [535 - 538]
Pages: 4
DOI: 10.2174/1570178054640796
Price: $65

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