First Microwave-Assisted Synthesis of 3-Substituted Isocoumarins

Author(s): K. M. Khan, S. Ahmed, Z. A. Khan, M. Rani, S. Perveen, M. I. Choudhary, Atta-ur-Rahman.

Journal Name: Letters in Organic Chemistry

Volume 2 , Issue 6 , 2005

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A microwave-assisted, environment friendly, high yielding, time saving synthesis of medicinally important 3-substituted isocoumarins was carried out in a single step by the direct condensation of homophthalic acid with aryol and acyl chlorides under the solvent-free conditions without any solid support. The synthesized isocoumarins were structurally characterized by microanalysis, 1H-NMR, EI, IR and UV.

Keywords: microwave-irradiation, homophthalic acid, substituted isocoumarins

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Article Details

Year: 2005
Page: [532 - 534]
Pages: 3
DOI: 10.2174/1570178054640813
Price: $58

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