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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of 14-Membered Ring Jaspamide Derivatives

Author(s): S. Celanire, C. Descamps-Francois, B. Lesur, G. Guillaumet and B. Joseph

Volume 2, Issue 6, 2005

Page: [528 - 531] Pages: 4

DOI: 10.2174/1570178054640697

Price: $65

Abstract

Two synthetic approaches of simpler jaspamide derivatives were investigated. The ring closure step was attempted either by RCM or by macrolactonisation. 14-Membered ring derivatives 15-16 were prepared by final macrolactonisation using Yamaguchi reagent.

Keywords: alkaloid, macrocycle, olefin metathesis, macrolactonisation


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