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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Efficient Chemical Synthesis of Sialic Acid Related Oligosaccharides

Author(s): C. Zhao, X. Zhen, H. Zhang and Y. Ding

Volume 2, Issue 6, 2005

Page: [521 - 523] Pages: 3

DOI: 10.2174/1570178054640732

Price: $65

Abstract

A very efficient strategy for the chemical synthesis of the sialyl Lewis X tetrasaccharide is reported. Starting from four simple monosaccharide building blocks, sialyl Lewis X was obtained in seven steps. By using similar strategy, sialyl LacNAc and sulfated sialyl LacNAc trisaccharides were also synthesized.

Keywords: tetrasaccharide, inflammation, monosaccharide, sialylation, hydrogenation


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