Efficient Chemical Synthesis of Sialic Acid Related Oligosaccharides

Author(s): C. Zhao, X. Zhen, H. Zhang, Y. Ding.

Journal Name: Letters in Organic Chemistry

Volume 2 , Issue 6 , 2005

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A very efficient strategy for the chemical synthesis of the sialyl Lewis X tetrasaccharide is reported. Starting from four simple monosaccharide building blocks, sialyl Lewis X was obtained in seven steps. By using similar strategy, sialyl LacNAc and sulfated sialyl LacNAc trisaccharides were also synthesized.

Keywords: tetrasaccharide, inflammation, monosaccharide, sialylation, hydrogenation

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Article Details

Year: 2005
Page: [521 - 523]
Pages: 3
DOI: 10.2174/1570178054640732
Price: $65

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