Abstract
The allylic alcohol of the side-chain of larixol was converted into an exo 1,3-diene through trifluoroacetylation followed by palladium-catalyzed elimination; this allowed the introduction of a benzoquinone pharmacophore on this labdane platform in one-pot from allylic trifluoroacetates.
Keywords: diene, allylic trifluoroacetate, larixol, quinone, labdane
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