Abstract
Molecular chaperones are one of the most important cell defense mechanisms against protein aggregation and misfolding. These specialized proteins bind non-native states of other proteins and assist them in reaching a correctly folded and functional conformation. Chaperones also participate in protein translocation by membranes, in the stabilization of unstable protein conformers and regulatory factors, in the delivery of substrates for proteolysis and in the recovery of proteins from aggregates.
Keywords: molecular chaperones, heat shock proteins, hsp70, chaperonin
Protein & Peptide Letters
Title: Protein Folding Assisted by Chaperones
Volume: 12 Issue: 3
Author(s): Julio C. Borges and Carlos H.I. Ramos
Affiliation:
Keywords: molecular chaperones, heat shock proteins, hsp70, chaperonin
Abstract: Molecular chaperones are one of the most important cell defense mechanisms against protein aggregation and misfolding. These specialized proteins bind non-native states of other proteins and assist them in reaching a correctly folded and functional conformation. Chaperones also participate in protein translocation by membranes, in the stabilization of unstable protein conformers and regulatory factors, in the delivery of substrates for proteolysis and in the recovery of proteins from aggregates.
Export Options
About this article
Cite this article as:
Borges C. Julio and Ramos H.I. Carlos, Protein Folding Assisted by Chaperones, Protein & Peptide Letters 2005; 12 (3) . https://dx.doi.org/10.2174/0929866053587165
DOI https://dx.doi.org/10.2174/0929866053587165 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Plasticity and Maintenance of Hematopoietic Stem Cells During Development
Recent Patents on Biotechnology Analysis the Effectiveness of Oral Massage Using Sono-elastography
Neuroscience and Biomedical Engineering (Discontinued) Medicinal Chemistry Approaches of Controlling Gastrointestinal Side Effects of Non-Steroidal Anti-Inflammatory Drugs. Endogenous Protective Mechanisms and Drug Design
Medicinal Chemistry Reflecting Back to Bring Nitric Oxide Research to the Laboratory
Current Medicinal Chemistry Phosphonic Esters and their Application of Protease Control
Current Pharmaceutical Design New Vaccines and Delivery Strategies for Adult Immunization
Current Immunology Reviews (Discontinued) Natural Coumarins as a Novel Class of Neuroprotective Agents
Mini-Reviews in Medicinal Chemistry Carbon Nanotube: A Versatile Carrier for Various Biomedical Applications
Drug Delivery Letters Cross-Talk Between TGF-β and NADPH Oxidases During Liver Fibrosis and Hepatocarcinogenesis
Current Pharmaceutical Design Current Treatment Strategies for Hepatocellular Carcinoma
Current Cancer Therapy Reviews Heparin Derivatives as Angiogenesis Inhibitors
Current Pharmaceutical Design Prophylactic Potential of Conventional and Supercritical Garlic Extracts to Alleviate Diet Related Malfunctions
Recent Patents on Food, Nutrition & Agriculture What Can Neuroscience Tell Us About the Potential of Psychedelics in Healthcare? How the Neurophenomenology of Psychedelics Research Could Help us to Flourish Throughout Our Lives, as Well as to Enhance Our Dying
Current Drug Abuse Reviews A Review of Light Sources and Enhanced Targeting for Photodynamic Therapy
Current Medicinal Chemistry Polymeric Nanoparticles for Ophthalmic Drug Delivery: An Update on Research and Patenting Activity
Recent Patents on Nanomedicine Aquaporins and Glia
Current Neuropharmacology Microfluidic Hydrodynamic Cell Separation: A Review
Micro and Nanosystems JLK Inhibitors: Isocoumarin Compounds as Putative Probes to Selectively Target the γ-Secretase Pathway
Current Alzheimer Research Potential Disease Targets for Drugs that Disrupt Protein - Protein Interactions of Grb2 and Crk Family Adaptors
Current Pharmaceutical Design V-ATPase Subunit Interactions: The Long Road to Therapeutic Targeting
Current Protein & Peptide Science