Recent Advances in the Synthesis of C-linked Glycoconjugates

Author(s): Elisabeth v. Moos, Robert N. Ben.

Journal Name: Current Topics in Medicinal Chemistry

Volume 5 , Issue 14 , 2005

Abstract:

During the last five years, the scientific community has seen a dramatic increase in the number of synthetic methods or strategies to prepare C-linked glycoconjugates. One reason for this increase is that the biological significance and roles of many O- and N-linked glyconconjugates has become evident. This review will summarize the biological importance of glycoconjugates and outline recent advances in the preparation of C-linked glycoconjugates that have appeared in the literature since the new millennium.

Keywords: Asparagine, double-bond isomerization, Ramberg-Backlund rearrangement, Tebbe/Claisen approach, C-Mannosyltryptophan

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Article Details

VOLUME: 5
ISSUE: 14
Year: 2005
Page: [1351 - 1361]
Pages: 11
DOI: 10.2174/156802605774643024
Price: $58

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