Design Features that Affect Psychopharmacology Trials

Author(s): Arif Khan, Kelly Schwartza.

Journal Name: Letters in Drug Design & Discovery

Volume 2 , Issue 7 , 2005

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Abstract:

The patients psychiatric diagnoses play a large role in the design and outcome of psychopharmacology clinical trials. Among antidepressant trials, magnitude of placebo response, initial severity of depression, dosing regimen, number of treatment arms and duration of trial, choice of rating scales, and sex of the patient may influence antidepressant trial outcome.

Keywords: investigational psychopharmacological agent, Antidepressant, placebo, Clinical Trials, obsessive compulsive disorder (OCD)

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Article Details

VOLUME: 2
ISSUE: 7
Year: 2005
Page: [546 - 550]
Pages: 5
DOI: 10.2174/157018005774479140
Price: $58