Hylins: Bombinins H Structurally Related Peptides from the Skin Secretion of the Brazilian Tree-Frog Hyla biobeba

Author(s): Mariana S. Castro, Rubens H. Matsushita, Antonio Sebben, Marcelo V. Sousa, Wagner Fontes.

Journal Name: Protein & Peptide Letters

Volume 12 , Issue 1 , 2005

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Two hemolytic peptides were isolated from the skin secretion of the Brazilian Hylidae frog Hyla biobeba, using reversed-phase chromatographic procedures. Hylins b1 and b2 exhibit short linear polypeptide chains, a large number of hydrophobic residues, amidated C-termini and hemolytic properties. These two novel peptides are the first examples of bombinins H-like peptides isolated from anurans species not related to Bombina species.

Keywords: amphibian, hyla, skin secretion, hemolytic peptides, hylins

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Article Details

Year: 2005
Page: [89 - 93]
Pages: 5
DOI: 10.2174/0929866053405977

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