Chemokine Signaling Defines Novel Targets for Therapeutic Intervention

Author(s): Jose M. Rodriguez-Frade, Carlos Martinez-A., Mario Mellado.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 5 , Issue 9 , 2005

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Members of the human chemokine family are considered a suitable target for therapeutic intervention, as they have a fundamental role in several important human diseases. Here we outline potential new areas of intervention based on recent findings on chemokine receptor function.

Keywords: chemokine receptors, inflammatory cytokines, g protein-coupled receptors (gpcr), polymorphism, hiv infection, jak/stat pathway

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Article Details

Year: 2005
Page: [781 - 789]
Pages: 9
DOI: 10.2174/1389557054867084
Price: $58