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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

One-Pot Regioselective Green Synthesis of Novel Quinolines Using a Neat Reaction Technology

Author(s): Mazaahir Kidwai and Vikas Bansal

Volume 4, Issue 7, 2007

Page: [519 - 523] Pages: 5

DOI: 10.2174/157017807782006263

Price: $65

Abstract

A convenient eco-friendly procedure has been developed for the synthesis of novel quinoline derivatives by a simple one-pot reaction of substituted anilines with β-ketoesters under microwave irradiation without any solvent. A comparative study of reaction on solid support versus neat reaction is done. Neat reaction technology gives better yield in shorter reaction times and also cuts down the usage of solvent.

Keywords: Quinolines, regioselective, microwaves, green chemistry, solid support and neat reaction


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