One-Pot Regioselective Green Synthesis of Novel Quinolines Using a Neat Reaction Technology

Author(s): Mazaahir Kidwai, Vikas Bansal.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 7 , 2007


A convenient eco-friendly procedure has been developed for the synthesis of novel quinoline derivatives by a simple one-pot reaction of substituted anilines with β-ketoesters under microwave irradiation without any solvent. A comparative study of reaction on solid support versus neat reaction is done. Neat reaction technology gives better yield in shorter reaction times and also cuts down the usage of solvent.

Keywords: Quinolines, regioselective, microwaves, green chemistry, solid support and neat reaction

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Article Details

Year: 2007
Page: [519 - 523]
Pages: 5
DOI: 10.2174/157017807782006263
Price: $58

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