An Efficient Novel Ligand for Copper-Catalyzed Formation of Diaryl Ethers

Author(s): Yinghua Yang, Xiangrui Jiang, Lei Ao, Shengyi Dong, Xiumei Wu, Hualiang Jiang, Yu Zhao.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 7 , 2007

Abstract:

1-Phenylbutane-1,3-dione was found to be an efficient novel ligand for copper-catalyzed formation of diaryl ethers. With this ligand methyl 4-iodobenzoate reacted with various phenols to give the corresponding diaryl ethers with reasonable yields and efficiency. The optimized reaction was carried out at 100 °C using 1,4-dioxane as solvent, Cs2CO3 as base, CuI as the catalyst and 1-phenylbutane-1,3-dione as the ligand.

Keywords: Diaryl ether, 1-Phenylbutane-1,3-dione, Ullmann coupling reaction, Methyl 4-iodobenzoate, CuI, Coppercatalyzed

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 4
ISSUE: 7
Year: 2007
Page: [491 - 494]
Pages: 4
DOI: 10.2174/157017807782006281
Price: $58