Recent Developments in the Understanding of Nuclear Protein Import

Author(s): S.M. Liu, W.M. Liu.

Journal Name: Protein & Peptide Letters

Volume 14 , Issue 7 , 2007

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Abstract:

The process of nucleocytoplasmic exchange of various macromolecules and metabolites between the nuclear and cytoplasmic compartment is crucial for cell function and survival. It is also closely involved with several pathogeneses including cancer and viral infections. Here, we will discuss the current understanding of the classical nuclear import pathway and the factors that are essential for this process.

Keywords: Nuclear transport, ran switch, importin, influenza

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Article Details

VOLUME: 14
ISSUE: 7
Year: 2007
Page: [723 - 733]
Pages: 11
DOI: 10.2174/092986607781483895
Price: $58