PrTX-I, a non-catalytic and myotoxic Lys49-PLA2 from Bothrops pirajai venom has been crystallized alone and in complex with bromophenacyl bromide (BPB), α-tocopherol and α-tocopherol acetate inhibitors. These crystals have shown to diffract X-rays between 2.34 and 1.65 Å resolution. All complexes crystals are isomorphous and belong to the space group P21 whereas native PrTX-I crystals belong to the P3121.
Keywords: Crystallization, X-ray crystallography, Lys49-phospholipase A2, Bothrops pirajai venom, myotoxity, pbromophenacyl bromide, p-BPB, α-tocopherol, vitamin E
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