Letters in Drug Design & Discovery

G. Perry
University of Texas
San Antonio, TX
USA
Email: lddd@benthamscience.org

Back

Preparation and Biological Activities of Heteroarotinoids

Author(s): Akimori Wada, Yukari Mizuguchi, Hiromi Miyake, Miki Niihara, Masayoshi Ito, Kimie Nakagawa, Toshio Okano.

Abstract:

Retinoic acid analogs containing an aromatic ring fixed between the 5 and 8 positions of retinoic acid, were synthesized by a palladium-catalyzed cross-coupling reaction between boronic acid and an alkenyltriflate or alkenyliodide. The biological activities of the retinoic acid analogs were evaluated.

Keywords: Heteroarotinoid, Boronic acid, Coupling reaction, RAR, RXR

Order Reprints Order Eprints Rights & PermissionsPrintExport

Article Details

VOLUME: 4
ISSUE: 6
Year: 2007
Page: [442 - 445]
Pages: 4
DOI: 10.2174/157018007781387827
Price: $58