Bacteriorhodopsin Analogue from Indolic Chromophores

Author(s): Prasanta Kumar Hota, Anil Kumar Singh.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 4 , 2007

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Abstract:

A new analogue of bacteriorhodopsin (bR) was prepared by allowing bacterioopsin (bOP), the apo-protein of bR to interact with (2Z,4E)-3-chloro-5-(1H-indol-3-yl)-2,4-pentadienal as chromophore. It was characterised for its opsin shift, stability, light-induced pH change and fluorescence emission. Indolic aldehydes viz. 1H-indole-3-carboxaldehyde and (2Z,4E)-3-chloro-5-[1-(phenylsulfonyl)-1H-indol-3-yl]-2,4-pentadienal did not bind bOP.

Keywords: Bacteriorhodopsin, Indole, Bacteriorhodopsin analogues, Opsin shift, Rhodopsins

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Article Details

VOLUME: 4
ISSUE: 4
Year: 2007
Page: [300 - 305]
Pages: 6
DOI: 10.2174/157017807781024228
Price: $65

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