Synthesis of Gallocatechin-3-Gallate Analogues

Author(s): Nadia Vaiana, Luca Rizzi, Maria G. Pezzano, Roberto Restelli, Filippo Rota, Silvia Stefanini, Silvia Vicentini, Sergio Romeo.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 4 , 2007

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Abstract:

The influence of substituents on the yields of the synthesis of seven catechines analogues has been studied. 3-Flavene formation is favoured by electron donors substituents on the A and B rings. Yields of the hydroboration reaction are increased by electron donor substituents on the A ring, while substituents on the B ring do not affect the reaction outcome.

Keywords: Gallocatechin, catechins, total synthesis, structure-reactivity study, EGCG

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Article Details

VOLUME: 4
ISSUE: 4
Year: 2007
Page: [288 - 291]
Pages: 4
DOI: 10.2174/157017807781024291
Price: $65

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