Lipase Catalysed Kinetic Resolution of 2-Nitroalcohol: Total Synthesis of Taxol Side Chain and (-)-Bestatin

Author(s): Naminita Gogoi, Jagat C. Borah, Joshodeep Boruwa, Nabin C. Barua.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 4 , 2007

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2-Nitroalcohols were efficiently resolved by Lipase catalysed transesterification process. This protocol was successfully applied to the synthesis of taxol side chain and (-)-bestatin in overall yields of 40% and 20% respectively.

Keywords: Taxol Side Chain, (-)-Bestatin, lipase catalysed kinetic resolution

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Article Details

Year: 2007
Page: [234 - 235]
Pages: 2
DOI: 10.2174/157017807781024192
Price: $65

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