Synthesis of the C-13 Side-Chain of Taxol

Author(s): Jagat C. Borah, Joshodeep Boruwa, Nabin C. Barua.

Journal Name: Current Organic Synthesis

Volume 4 , Issue 2 , 2007

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Abstract:

This review covers different synthetic routes to the C-13 side-chain of taxol the most potent antimicrotubule agent first isolated from Texus bravifolia and later on from several other species of Taxus. The different approaches reported for the syntheses of the C-13 side-chain of taxol are catagorized on the synthetic strategies applied.

Keywords: Taxol, 10-DAB, C-13 side-chain, total synthesis, antimicotubule

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Article Details

VOLUME: 4
ISSUE: 2
Year: 2007
Page: [175 - 199]
Pages: 25
DOI: 10.2174/157017907780598899
Price: $58

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