The Blomia tropicalis Allergens

Author(s): Kaw Yan Chua, Nge Cheong, I-Chun Kuo, Bee Wah Lee, Fong Cheng Yi, Chiung-Hui Huang, Lip Nyin Liew.

Journal Name: Protein & Peptide Letters

Volume 14 , Issue 4 , 2007

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Blomia tropicalis allergens are the most important mite allergens in tropical regions. Most of them only have 30-40% sequence identity with their Dermatophagoides counterparts and they share low IgE cross reactivity and exhibit different immunobiology. Unlike the pyroglyphid counterparts, Blo t 5 is the major allergen whereas Blo t 1 only has modest allergenicity.

Keywords: Dermatophagoides, cysteine protease, house dust mite allergens, IgE, RACE cDNA amplification

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Article Details

Year: 2007
Page: [325 - 333]
Pages: 9
DOI: 10.2174/092986607780363862
Price: $65

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PDF: 17