Raxofelast, (±)5-(Acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic Acid: A New Antioxidant to Modulate the Inflammatory Response During Ischemia-Reperfusion Injury and Impaired Wound Healing

Author(s): A. Bitto , L. Minutoli , F. Squadrito , F. Polito , D. Altavilla .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 7 , Issue 3 , 2007

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Abstract:

Raxofelast, also named IRFI 016 or (±)5-(Acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic acid, belongs to a family of novel molecules designed with the aim to maximize antioxidant potency of phenols related to Vitamin E ( α-tocopherol). This review will focus on the antioxidant and radical scavenging activity of this new promising compound.

Keywords: Raxofelast, inflammation, ischemia/reperfusion injury, wound healing, diabetes, safety

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Article Details

VOLUME: 7
ISSUE: 3
Year: 2007
Page: [339 - 343]
Pages: 5
DOI: 10.2174/138955707780059835
Price: $58

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