Microwave-Promoted Ring Opening Reaction of Azalactones

Author(s): Ricardo H. Valdes, Donato A.G. Aranda, Heiddy M. Alvarez, Octavio A.C. Antunes.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 1 , 2007

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Abstract:

α,β-Dehydroamino amides are important intermediates for the synthesis of biologically active molecules. A rapid procedure is reported for the synthesis of α,β-dehydroamino amides from azalactones under MW radiation. Azalactones were produced via Erlenmeyer reaction and submitted to ring opening reactions under MW during 15-30 min. Over 90% yields were obtained.

Keywords: α,β-Dehydroamino amides, azalactones, ring opening, microwave irradiation

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Article Details

VOLUME: 4
ISSUE: 1
Year: 2007
Page: [35 - 38]
Pages: 4
DOI: 10.2174/157017807780037360

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